Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090537 | 0.86 | KDM4E (0.71) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28090837 | 0.85 | ALDH1A1 (0.57) | MAPTALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL28090536 | 0.77 | SMN1; SMN2 (0.50) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL28090870 | 0.77 | KDM4E (0.55) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28090599 | 0.77 | MAPT (0.58) | MAPTALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL28090832 | 0.77 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28832969 | 0.77 | KDM4E (0.47) | MAPTALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL28090875 | 0.74 | ALDH1A1 (0.69) | MAPTALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL6314635 | 0.73 | PKM (0.71) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1759145 | 0.72 | KDM4E (0.77) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187923-A | 2 aryl 4 aroyl triazole compounds and application thereof | 沈阳药科大学 | 2016-12-07 | — | — | CN | disclosed |