Acetophenone

Acetophenone

SCHEMBL28090652

CC(=O)c1ccccc1.CC(C)c1ccc2sc3ccccc3c(=O)c2c1C(C)C

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.41
RAB9A P51151 4/20 0.41
HPGD P15428 2/20 0.41
NPC1 O15118 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
ALDH1A1 P00352 4/20 0.39
GAA P10253 2/20 0.39
MEN1 O00255 2/20 0.39
POLB P06746 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 4/20 0.39
NPSR1 Q6W5P4 2/20 0.39
MAPK1 P28482 2/20 0.38
LMNA P02545 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156858 0.89 MAPT (0.50) MAPTRAB9AHPGDNPC1CYP1A2
Phosphine SCHEMBL28097474 0.87 MAPT (0.49) MAPTRAB9AHPGDNPC1CYP1A2
SCHEMBL28080045 0.86 MAPT (0.48) MAPTRAB9AHPGDNPC1CYP1A2
SCHEMBL28090690 0.81 MAPT (0.44) MAPTRAB9AHPGDNPC1CYP1A2
Xanthone SCHEMBL28129970 0.80 MAOA (0.44) MAPTRAB9AHPGDNPC1CYP1A2
Acetophenone SCHEMBL10711555 0.79 MAPT (0.49) MAPTRAB9AHPGDNPC1CYP1A2
SCHEMBL9003201 0.79 MAPT (0.41) MAPTRAB9AHPGDNPC1CYP1A2
Benzophenone SCHEMBL5072184 0.78 GABRA1 (0.44) MAPTRAB9AHPGDNPC1CYP1A2
Acetone SCHEMBL1615361 0.77 MAPT (0.46) MAPTRAB9AHPGDNPC1CYP1A2
SCHEMBL3208280 0.77 MAOA (0.52) MAPTRAB9AHPGDNPC1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103992331-B Polymerizable chiral compound, polymerizable liquid crystal compound, liquid crystal liquid crystal property macromolecule and optically anisotropic body 日本瑞翁株式会社 2016-08-17 CN disclosed