Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MMP1 | P03956 | 5/20 | 0.56 |
| ▸ | MMP2 | P08253 | 5/20 | 0.56 |
| ▸ | MMP9 | P14780 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL28832967 | 0.97 | ALDH1A1 (0.59) | ALDH1A1TAAR1HPGDSMN1; SMN2MMP1 | |
| SCHEMBL297599 | 0.93 | ALDH1A1 (0.67) | ALDH1A1TAAR1HPGDSMN1; SMN2MMP1 | |
| SCHEMBL6574321 | 0.88 | ALDH1A1 (0.60) | ALDH1A1TAAR1HPGDSMN1; SMN2MMP1 | |
| SCHEMBL6209769 | 0.83 | TAAR1 (0.69) | ALDH1A1TAAR1HPGDPOLBTGM2 | |
| Acrylamide SCHEMBL28802284 | 0.83 | TGM2 (0.60) | ALDH1A1SMN1; SMN2MMP1MMP2MMP9 | |
| Acrylamide SCHEMBL8009772 | 0.82 | FFAR1 (0.52) | ALDH1A1TAAR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL5494060 | 0.82 | TGM2 (0.65) | ALDH1A1TAAR1HPGDSMN1; SMN2POLB | |
| SCHEMBL7269650 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TAAR1HPGDSMN1; SMN2MMP1 | |
| SCHEMBL5491392 | 0.81 | TGM2 (0.68) | ALDH1A1TAAR1HPGDSMN1; SMN2POLB | |
| SCHEMBL16594132 | 0.80 | ESRRG (0.50) | ALDH1A1TAAR1HPGDSMN1; SMN2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105874016-B | Liquid polymerizable composition and its purposes for being used to manufacture optical goods comprising acid anhydride derivatives monomer and the mineral nano particle being dispersed therein | 依视路国际公司 | 2018-12-25 | — | — | CN | disclosed |
| CN-105874016-A | Liquid polymerizable composition comprising an anhydride derivative monomer and mineral nanoparticles dispersed therein, and its use to manufacture an optical article | 埃西勒国际通用光学公司 | 2016-08-17 | — | — | CN | disclosed |