SCHEMBL6209769

SCHEMBL6209769

C=CC(=O)NCCCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.69
TGM2 P21980 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
GAA P10253 2/20 0.60
NPC1 O15118 2/20 0.60
HPGD P15428 2/20 0.60
RAB9A P51151 1/20 0.60
EPHX2 P34913 1/20 0.58
LMNA P02545 3/20 0.57
KMT2A Q03164 2/20 0.57
KDM4E B2RXH2 1/20 0.57
EPHX1 P07099 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
POLB P06746 1/20 0.57
CNR1 P21554 1/20 0.55
ALDH1A1 P00352 3/20 0.54
HTT P42858 2/20 0.54
MAPT P10636 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5494060 0.95 TGM2 (0.65) TAAR1TGM2L3MBTL1GAANPC1
SCHEMBL5491392 0.93 TGM2 (0.68) TAAR1TGM2L3MBTL1GAANPC1
SCHEMBL297599 0.89 ALDH1A1 (0.67) TAAR1TGM2NPC1HPGDRAB9A
SCHEMBL10808724 0.87 TGM2 (0.60) TAAR1TGM2L3MBTL1GAANPC1
SCHEMBL105521 0.85 GAA (0.57) TAAR1TGM2GAAKDM4E
SCHEMBL8980074 0.84 TAAR1 (0.71) TAAR1L3MBTL1GAANPC1HPGD
SCHEMBL10362383 0.84 TGM2 (0.60) TAAR1TGM2L3MBTL1GAANPC1
Acrylamide SCHEMBL28090758 0.83 ALDH1A1 (0.59) TAAR1TGM2NPC1HPGDRAB9A
SCHEMBL19854544 0.82 THRA (0.51) TAAR1TGM2L3MBTL1GAAEPHX2
SCHEMBL11124846 0.81 TAAR1 (1.00) TAAR1L3MBTL1GAANPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1069943-B1 LARGE PORE VOLUME COMPOSITE MINERAL OXIDE BEADS, THEIR PREPARATION AND THEIR APPLICATIONS FOR ADSORPTION AND CHROMATOGRAPHY PALL CORP (US) 2005-07-06 EP claimed
EP-1071500-B1 SMALL DENSE MICROPOROUS SOLID SUPPORT MATERIALS, THEIR PREPARATION, AND USE FOR PURIFICATION OF LARGE MACROMOLECULES AND BIOPARTICLES CIPHERGEN BIOSYSTEMS INC (US) 2005-03-02 EP claimed
US-6613234-B2 Stability; titanium, zirconium, hafnium oxide CIPHERGEN BIOSYSTEMS, INC. 2003-09-02 US claimed
US-20020104801-A1 SMALL DENSE MICROPOROUS SOLID SUPPORT MATERIALS, THEIR PREPARATION,AND USE FOR PURIFICATION OF LARGE MACROMOLECULES AND BIOPARTICLES Life Technologies Corporation 2002-08-08 US claimed
US-20020005383-A1 LARGE PORE VOLUME COMPOSITE MINERAL OXIDE BEADS, THEIR PREPARATION AND THEIR APPLICATIONS FOR ADSORPTION AND CHROMATOGRAPHY Life Technologies Corporation 2002-01-17 US claimed
EP-1071500-A1 SMALL DENSE MICROPOROUS SOLID SUPPORT MATERIALS, THEIR PREPARATION, AND USE FOR PURIFICATION OF LARGE MACROMOLECULES AND BIOPARTICLES Life Technologies, Inc. (US) 2001-01-31 EP claimed
EP-1069943-A1 LARGE PORE VOLUME COMPOSITE MINERAL OXIDE BEADS, THEIR PREPARATION AND THEIR APPLICATIONS FOR ADSORPTION AND CHROMATOGRAPHY LIFE TECHNOLOGIES, INC. (US) 2001-01-24 EP claimed
WO-1999051316-A1 SMALL DENSE MICROPOROUS SOLID SUPPORT MATERIALS, THEIR PREPARATION, AND USE FOR PURIFICATION OF LARGE MACROMOLECULES AND BIOPARTICLES LIFE TECHNOLOGIES, INC. (US) 1999-10-14 WO claimed
WO-1999051335-A1 LARGE PORE VOLUME COMPOSITE MINERAL OXIDE BEADS, THEIR PREPARATION AND THEIR APPLICATIONS FOR ADSORPTION AND CHROMATOGRAPHY LIFE TECHNOLOGIES, INC. (US) 1999-10-14 WO claimed
CN-116444370-A Preparation method of alpha, beta-unsaturated carboxylic acid derivative 大连理工常熟研究院有限公司 2023-07-18 CN disclosed
US-11492432-B2 Resin for nanoimprinting, laminate containing resin for nanoimprinting, printed board containing resin for nanoimprinting, and method for producing nanoimprint substrate JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2022-11-08 US disclosed
CN-109053644-B Rapid synthesis method of biomass amine amide 南京农业大学 2022-07-15 CN disclosed
US-20210369731-A1 COVALENT TARGETING OF E3 LIGASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-12-02 US disclosed
CN-110938168-B Hydrophobic hydrogen bond enhanced hydrogel and preparation method thereof 天津大学 2021-09-07 CN disclosed
EP-0751810-A4 METHOD AND POROUS SUPPORT FOR REMOVING CONTAMINANTS HEMASURE INC (US) 1997-11-26 EP disclosed
US-5609763-A METAL OXIDE, CROSSLINKED HYDROPHOBIC ACRYLIC POLYMER, ADSORBING VIRAL INACTIVATING AGENTS FROM BLOOD HEMASURE, INC. (US) 1997-03-11 US disclosed
EP-0751810-A1 METHOD AND POROUS SUPPORT FOR REMOVING CONTAMINANTS HEMASURE, INC. (US) 1997-01-08 EP disclosed
US-5486293-A USING A CROSSLINKED HYDROPHOBIC POLYMER NETWORK OVERLAYING A POROUS MINERAL OXIDE MATRIX HEMASURE, INC. (US) 1996-01-23 US disclosed
WO-1995025574-A1 METHOD AND POROUS SUPPORT FOR REMOVING CONTAMINANTS HEMASURE, INC. (US) 1995-09-28 WO disclosed
EP-0329409-A2 Backfilling process Ciba Specialty Chemicals Water Treatments Limited (GB) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369731-A1 COVALENT TARGETING OF E3 LIGASES RNF114, RNF4, RNF168 TAAR1 4684/4885TGM2 3684/4885L3MBTL1 421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.