Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 13/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 13/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 11/20 | 0.48 |
| ▸ | CDK2 | P24941 | 11/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 11/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 2/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | MGMT | P16455 | 2/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146063 | 0.86 | CDK1 (0.61) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL6897929 | 0.83 | CDK1 (0.63) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL29387231 | 0.83 | PDPK1 (0.59) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL453220 | 0.83 | PDPK1 (0.59) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL2060155 | 0.83 | PDPK1 (0.51) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL27818523 | 0.82 | PDPK1 (0.54) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL30443707 | 0.79 | PDPK1 (0.59) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL6334784 | 0.77 | PDPK1 (0.49) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL27673194 | 0.77 | PIN1 (0.63) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL29592683 | 0.76 | PDPK1 (0.59) | PDPK1GDACDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530130-B | A kind of method preparing adefovir ester | 河南师范大学 | 2016-08-24 | — | — | CN | disclosed |