Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.34 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28091366 | 0.84 | KDM1A (0.45) | MAPTKDM1ALMNAPIN1 | |
| SCHEMBL28833015 | 0.82 | KDM1A (0.43) | MAPTKDM1ALMNASMN1; SMN2HIF1A | |
| SCHEMBL28228966 | 0.81 | ACHE (0.39) | MAPTBCHEACHEGRIN1GRIN2A | |
| SCHEMBL28833010 | 0.77 | KMT2A (0.39) | RXFP1ACHELMNASMN1; SMN2 | |
| SCHEMBL28732552 | 0.70 | ACP1 (0.43) | MAPTKDM1ALMNAPOLBHTT | |
| SCHEMBL29375294 | 0.66 | PIN1 (0.38) | KDM1AHIF1APIN1 | |
| SCHEMBL22401515 | 0.66 | PIN1 (0.38) | KDM1AHIF1APIN1 | |
| SCHEMBL28091133 | 0.64 | MAPT (0.44) | MAPTKDM1ALMNAPOLBHTT | |
| SCHEMBL30540334 | 0.64 | NT5E (0.60) | SLC2A1SLC2A3SLC2A4LMNAPOLB | |
| SCHEMBL26390753 | 0.64 | HTT (0.73) | MAPTCDK2CLK1NPSR1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859620-A | 6-trichloromethyl phenanthridine compounds and preparation method and application thereof | 大连理工大学 | 2016-08-17 | — | — | CN | disclosed |