Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28228966 | 0.89 | ACHE (0.39) | KMT2AACHEHDAC3HDAC4HDAC1 | |
| SCHEMBL28091119 | 0.82 | KMT2A (0.48) | KMT2AACHEGPR3GLAKDM4E | |
| SCHEMBL28091313 | 0.82 | MAOA (0.46) | KMT2AACHEGPR3MEN1HCRTR1 | |
| SCHEMBL12481032 | 0.78 | MAOA (0.44) | KMT2ARXFP1ACHEGPR3GRM2 | |
| SCHEMBL28833015 | 0.77 | KDM1A (0.43) | KMT2AADORA2AMEN1ABCG2GLA | |
| SCHEMBL28091075 | 0.77 | MAPT (0.34) | RXFP1ACHESMN1; SMN2LMNA | |
| SCHEMBL3854784 | 0.75 | GPR3 (0.66) | KMT2AGPR3ADORA2AMEN1HCRTR1 | |
| SCHEMBL12480311 | 0.75 | KMT2A (0.41) | KMT2ARXFP1ACHEGPR3HDAC3 | |
| SCHEMBL28091354 | 0.73 | ESR1 (0.44) | ABCG2KDM4EL3MBTL1 | |
| SCHEMBL31414194 | 0.72 | MAPT (0.37) | KMT2ARXFP1ACHEGPR3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859620-A | 6-trichloromethyl phenanthridine compounds and preparation method and application thereof | 大连理工大学 | 2016-08-17 | — | — | CN | disclosed |