Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GPR3 | P46089 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28833010 | 0.82 | KMT2A (0.39) | KMT2AGPR3MAOAMAOBKDM4E | |
| SCHEMBL28833015 | 0.82 | KDM1A (0.43) | KMT2AKDM4EALDH1A1ATMGLA | |
| SCHEMBL11101886 | 0.79 | MAOA (0.59) | KMT2AGPR3MAOAMAOBKDM4E | |
| SCHEMBL12142339 | 0.78 | GPR3 (0.54) | KMT2AGPR3MAOAMAOBKDM4E | |
| SCHEMBL28865531 | 0.74 | NQO2 (0.47) | KMT2AKDM4EHPGDSMN1; SMN2NQO2 | |
| SCHEMBL5720410 | 0.73 | MAOA (0.56) | KMT2AGPR3MAOAMAOBKDM4E | |
| SCHEMBL18869688 | 0.72 | GPR3 (0.47) | KMT2AGPR3MAOAMAOBKDM4E | |
| SCHEMBL516091 | 0.70 | TDP1 (0.59) | KMT2AGPR3MAOAMAOBKDM4E | |
| SCHEMBL19445500 | 0.68 | GPR3 (0.58) | KMT2AGPR3MAOAMAOBKDM4E | |
| SCHEMBL6683074 | 0.67 | CCNB2 (0.56) | KMT2AMAOAMAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859620-B | 6-trichloromethyl phenanthridine compounds and preparation method and application thereof | 大连理工大学 | 2018-07-13 | — | — | CN | claimed |
| CN-105859620-A | 6-trichloromethyl phenanthridine compounds and preparation method and application thereof | 大连理工大学 | 2016-08-17 | — | — | CN | claimed |
| CN-105859620-B | 6-trichloromethyl phenanthridine compounds and preparation method and application thereof | 大连理工大学 | 2018-07-13 | — | — | CN | disclosed |
| CN-105859620-B | 6-trichloromethyl phenanthridine compounds and preparation method and application thereof | 大连理工大学 | 2018-07-13 | — | — | CN | disclosed |
| CN-105859620-A | 6-trichloromethyl phenanthridine compounds and preparation method and application thereof | 大连理工大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-105859620-A | 6-trichloromethyl phenanthridine compounds and preparation method and application thereof | 大连理工大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-105859620-A | 6-trichloromethyl phenanthridine compounds and preparation method and application thereof | 大连理工大学 | 2016-08-17 | — | — | CN | disclosed |