Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199985 | 1.00 | ALDH1A1 (0.40) | ALDH1A1POLBLMNAHSD17B10ALOX15 | |
| SCHEMBL5200419 | 0.87 | CA2 (0.42) | ALDH1A1POLBLMNAHSD17B10ALOX15 | |
| SCHEMBL27625682 | 0.87 | HDAC1 (0.36) | ALDH1A1LMNAHSD17B10CHRM1AKR1A1 | |
| SCHEMBL5793752 | 0.84 | CA1 (0.44) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL27598398 | 0.84 | ZDHHC7 (0.46) | L3MBTL1CPB2KMT2A | |
| SCHEMBL11723542 | 0.84 | ZDHHC7 (0.46) | L3MBTL1CPB2KMT2A | |
| SCHEMBL27924536 | 0.83 | PPARA (0.39) | ALDH1A1POLBLMNAHSD17B10ALOX15 | |
| SCHEMBL8209757 | 0.82 | ALDH1A1 (0.40) | ALDH1A1POLBLMNAHSD17B10ALOX15 | |
| SCHEMBL3284678 | 0.81 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL28972736 | 0.81 | L3MBTL1 (0.51) | ALDH1A1POLBLMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960246-A | Novel cyclosporin derivatives and use thereof | 美国科技环球有限公司 | 2016-09-21 | — | — | CN | disclosed |