Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28227262 | 0.98 | TRPA1 (0.38) | TRPA1GSRNPC1CYP1A2CYP3A4 | |
| SCHEMBL7090878 | 0.80 | TRPA1 (0.44) | TRPA1GSRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28067361 | 0.79 | KCNH2 (0.41) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL7960668 | 0.77 | TRPA1 (0.46) | TRPA1GSRSLC6A4 | |
| SCHEMBL18982890 | 0.75 | TRPA1 (0.47) | TRPA1GSRSLC6A4ALDH1A1SLC6A2 | |
| SCHEMBL19173724 | 0.75 | TRPA1 (0.41) | TRPA1GSRCYP1A2CYP2D6TSHR | |
| SCHEMBL8749377 | 0.74 | NPC1 (0.40) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21280877 | 0.74 | TRPA1 (0.43) | TRPA1GSRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17288627 | 0.74 | MEN1 (0.51) | CYP1A2CYP2D6TSHRSLC6A4SMN1; SMN2 | |
| SCHEMBL6455092 | 0.74 | NPC1 (0.38) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108285482-A | Through modifying relaxain polypeptide and application thereof | 阿姆布埃克斯股份有限公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-101541955-B | Hybrid suppressor tRNA for vertebrate cells | AMBRX公司 | 2016-09-28 | — | — | CN | disclosed |