Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL911553 | 0.80 | DYRK1A (0.41) | KMT2AMEN1L3MBTL1MAPK1IKBKB | |
| SCHEMBL5942394 | 0.77 | HPGD (0.65) | HPGDSMN1; SMN2LRRK2GAATSHR | |
| SCHEMBL31701134 | 0.74 | SMN1; SMN2 (0.43) | HPGDSMN1; SMN2LRRK2GAATSHR | |
| SCHEMBL18556111 | 0.73 | L3MBTL1 (0.43) | HPGDSMN1; SMN2LRRK2GAATDP1 | |
| SCHEMBL31053616 | 0.72 | NOS2 (0.39) | SMN1; SMN2TDP1KMT2AMEN1RPS6KA5 | |
| SCHEMBL11812262 | 0.72 | GAA (0.51) | HPGDSMN1; SMN2GAATSHRNPC1 | |
| SCHEMBL1966363 | 0.72 | NOS2 (0.39) | SMN1; SMN2TDP1KMT2AMEN1RPS6KA5 | |
| SCHEMBL9042332 | 0.72 | L3MBTL1 (0.43) | HPGDSMN1; SMN2TSHRTDP1NPC1 | |
| SCHEMBL17377252 | 0.71 | ALDH1A1 (0.40) | HPGDSMN1; SMN2GAATSHRTDP1 | |
| SCHEMBL5942693 | 0.71 | HPGD (0.47) | HPGDSMN1; SMN2LRRK2GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980363-A | Aminopyrazolone Derivatives | 第三共株式会社 | 2016-09-28 | — | — | CN | disclosed |