Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAP2 | P11137 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810876 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4ECYP1A2XBP1 | |
| SCHEMBL13168431 | 0.83 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ECYP1A2XBP1 | |
| SCHEMBL8689272 | 0.76 | RAB9A (0.61) | ALDH1A1HPGDKDM4ETUBB4ATUBB | |
| SCHEMBL2956667 | 0.76 | ALDH1A1 (0.73) | ALDH1A1HPGDKDM4ECYP1A2XBP1 | |
| SCHEMBL5270788 | 0.73 | RAB9A (0.57) | ALDH1A1KDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL18320469 | 0.73 | KMT2A (0.69) | ALDH1A1HPGDGAARAB9ANPC1 | |
| SCHEMBL4741015 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KDM4ERAB9ANPC1MAPK1 | |
| SCHEMBL7673201 | 0.72 | ALDH1A1 (0.74) | ALDH1A1HPGDKDM4ECYP1A2XBP1 | |
| SCHEMBL7679486 | 0.72 | ALDH1A1 (0.60) | ALDH1A1HPGDKDM4ECYP1A2XBP1 | |
| SCHEMBL7387632 | 0.72 | RAB9A (0.49) | ALDH1A1HPGDKDM4EGAATUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240642-A1 | 1H-Indole-2-Carboxylic Acid Derivatives Useful As PPAR Modulators | SMITHKLINE BEECHAM CORPORATION (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100240642-A1 | 1H-Indole-2-Carboxylic Acid Derivatives Useful As PPAR Modulators | SMITHKLINE BEECHAM CORPORATION (US) | 2010-09-23 | — | — | US | disclosed |
| CN-101563322-A | 1H-indole-2-carboxylic acid derivatives useful as PPAR modulators | SMITHKLINE BEECHAM CORPORAITON (US) | 2009-10-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240642-A1 | 1H-Indole-2-Carboxylic Acid Derivatives Useful As PPAR Modulators | PPARD, PPARA, PPARG | ALDH1A1 402/4885HPGD 421/4885KDM4E 2514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.