SCHEMBL28092209

SCHEMBL28092209

CCCCCCCCOC(=O)c1ccccc1C(=O)OCCCCCCCC.CCOC(=O)CCCCCCCCC(=O)OCC

nearest known ligand 0.77

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.77
TSHR P16473 6/20 0.77
LMNA P02545 3/20 0.77
MAPK1 P28482 3/20 0.74
CYP3A4 P08684 2/20 0.74
TP53 P04637 1/20 0.74
L3MBTL1 Q9Y468 3/20 0.67
TDP1 Q9NUW8 2/20 0.67
KDM4E B2RXH2 3/20 0.63
HSD17B10 Q99714 2/20 0.63
POLB P06746 1/20 0.63
DGKA P23743 1/20 0.51
MAPT P10636 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
CYP4F2 P78329 1/20 0.49
CYP4A11 Q02928 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9298568 0.94 ALDH1A1 (0.82) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL1943177 0.94 ALDH1A1 (0.82) ALDH1A1TSHRLMNAMAPK1CYP3A4
Dibutyl Phthalate SCHEMBL10731020 0.93 ALDH1A1 (0.79) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL4255174 0.93 ALDH1A1 (0.79) ALDH1A1TSHRLMNAMAPK1CYP3A4
Dibutyl Sebacate SCHEMBL7768874 0.90 TSHR (0.69) ALDH1A1TSHRLMNAMAPK1CYP3A4
Dibutyl Phthalate SCHEMBL8962381 0.90 TSHR (0.78) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL10355198 0.90 TSHR (0.78) ALDH1A1TSHRLMNAMAPK1CYP3A4
Dibutyl Sebacate SCHEMBL5445113 0.90 TSHR (0.78) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL6402293 0.90 ALDH1A1 (0.90) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL782238 0.90 ALDH1A1 (0.90) ALDH1A1TSHRLMNAMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105992596-A Composition for accelerating penetration through skin, preparation for transdermal administration, and skin patch preparation 日东电工株式会社 2016-10-05 CN disclosed
CN-105939729-A Composition for accelerating penetration through skin, preparation for transdermal administration, and skin patch preparation 日东电工株式会社 2016-09-14 CN disclosed