Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28093092

CNCCN1CCCC1(C)C.N

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 3/20 0.43
PRMT6 Q96LA8 3/20 0.43
PRMT8 Q9NR22 2/20 0.43
PRMT1 Q99873 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12478392 0.98 CARM1 (0.45) CARM1PRMT6PRMT8PRMT1
Ammonia Solution, Strong SCHEMBL28794902 0.94 CARM1 (0.47) CARM1PRMT6PRMT8PRMT1
SCHEMBL20079275 0.78 CARM1 (0.45) CARM1PRMT6PRMT8PRMT1
SCHEMBL24577173 0.76 ADH1B (0.34)
SCHEMBL22102459 0.75 CARM1 (0.37) CARM1PRMT6PRMT8PRMT1
SCHEMBL9286726 0.74 BDKRB2 (0.30)
SCHEMBL2332652 0.72 ALOX15 (0.35)
SCHEMBL11868831 0.72 TSHR (0.31)
SCHEMBL16091005 0.72
SCHEMBL3657285 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103492404-B C-4' substituted macrolide derivatives 大正制药株式会社 2016-09-07 CN disclosed