SCHEMBL28093151

SCHEMBL28093151

CC(C)Cc1cc(CC(C)C)c(-c2ccc(O)cc2)c(CC(C)C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.53
GABRB2 P47870 2/20 0.53
TAAR1 Q96RJ0 3/20 0.40
SLC6A2 P23975 1/20 0.40
ESR1 P03372 3/20 0.39
ESR2 Q92731 2/20 0.39
SENP1 Q9P0U3 1/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
S1PR1 P21453 1/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28225281 0.86 SENP1 (0.42) GABRA1GABRB2TAAR1SLC6A2ESR1
SCHEMBL28329969 0.81 GABRA1 (0.59) GABRA1GABRB2TAAR1SLC6A2ESR1
SCHEMBL19261467 0.81 GABRA1 (0.47) GABRA1GABRB2TAAR1SLC6A2ESR1
SCHEMBL28049538 0.78 HMGCR (0.38) GABRA1GABRB2TAAR1SLC6A2ESR1
SCHEMBL28174185 0.77 TAAR1 (0.59) GABRA1GABRB2TAAR1SLC6A2ESR1
SCHEMBL28301640 0.75 GABRA1 (0.41) GABRA1GABRB2TAAR1SLC6A2ESR1
SCHEMBL1538588 0.74 GABRA1 (0.61) GABRA1GABRB2SLC6A2ESR1MAPT
SCHEMBL28251448 0.74 TAAR1 (0.67) GABRA1GABRB2TAAR1SLC6A2ESR1
SCHEMBL36323 0.74 TAAR1 (0.67) GABRA1GABRB2TAAR1SLC6A2ESR1
SCHEMBL6537139 0.73 HSD17B1 (0.49) ESR1ESR2SENP1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106029773-A Novel antiagglomerating agents for the production of polyisobutenes 巴斯夫东南亚有限公司 2016-10-12 CN disclosed