Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28932575 | 0.74 | HMGCR (0.46) | MEN1RECQLKMT2ATDP1THRB | |
| SCHEMBL19685198 | 0.72 | MEN1 (0.55) | MEN1RAD52RECQLKMT2ATDP1 | |
| SCHEMBL4656377 | 0.71 | TYR (0.52) | MEN1KMT2ATDP1KDM4EMAPT | |
| SCHEMBL6268956 | 0.70 | HTT (0.49) | MEN1KMT2A | |
| SCHEMBL133807 | 0.69 | — | — | |
| SCHEMBL2001188 | 0.67 | TDP1 (0.64) | MEN1RAD52RECQLKMT2ATDP1 | |
| SCHEMBL7228993 | 0.64 | — | — | |
| SCHEMBL929876 | 0.64 | — | — | |
| SCHEMBL633312 | 0.62 | TYR (0.65) | MEN1KMT2ATDP1MAPTALOX15 | |
| SCHEMBL30255614 | 0.62 | TYR (0.65) | MEN1KMT2ATDP1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980372-A | Functionalized benzopyran compounds and uses thereof | 诺沃根有限公司 | 2016-09-28 | — | — | CN | disclosed |