Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848639 | 0.93 | ALOX5 (0.54) | TYRHTTALOX5MEN1KMT2A | |
| SCHEMBL28932575 | 0.88 | HMGCR (0.46) | TYRHTTALOX5MEN1KMT2A | |
| SCHEMBL28045776 | 0.83 | TYR (0.50) | TYRHTTALOX5MEN1KMT2A | |
| SCHEMBL9056784 | 0.83 | TYR (0.50) | TYRHTTALOX5MEN1KMT2A | |
| SCHEMBL27973045 | 0.79 | TYR (0.42) | TYRHTTALOX5MEN1KMT2A | |
| SCHEMBL11060195 | 0.78 | ALOX5 (0.50) | TYRHTTALOX5MEN1KMT2A | |
| SCHEMBL156399 | 0.77 | TYR (0.65) | TYRHTTALOX5MEN1KMT2A | |
| SCHEMBL10671033 | 0.76 | ALOX5 (0.49) | TYRHTTALOX5MEN1KMT2A | |
| SCHEMBL9250407 | 0.75 | ALOX5 (0.44) | TYRHTTALOX5MEN1KMT2A | |
| SCHEMBL3382419 | 0.74 | TYR (0.63) | TYRHTTALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400691-A | Tropolone-substituted and hydroxyphenyl-substituted oligopeptides for depigmentation | BEIERSDORF AG (DE) | 2009-04-01 | — | — | CN | claimed |
| CN-101400691-A | Tropolone-substituted and hydroxyphenyl-substituted oligopeptides for depigmentation | BEIERSDORF AG (DE) | 2009-04-01 | — | — | CN | disclosed |
| EP-1996606-A1 | TROPOLONE- AND HYDROXYBENZENE-SUBSTITUTED OLIGOPEPTIDES FOR DEPIGMENTATION | Beiersdorf Aktiengesellschaft (DE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007101882-A1 | TROPOLONE- AND HYDROXYBENZENE-SUBSTITUTED OLIGOPEPTIDES FOR DEPIGMENTATION | BEIERSDORF AG (DE) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007101882-A1 | TROPOLONE- AND HYDROXYBENZENE-SUBSTITUTED OLIGOPEPTIDES FOR DEPIGMENTATION | BEIERSDORF AG (DE) | 2007-09-13 | — | — | WO | disclosed |