Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656377 | 0.88 | TYR (0.52) | HMGCRTYRMAPTHTTMEN1 | |
| SCHEMBL8848639 | 0.85 | ALOX5 (0.54) | TYRMAPTHTTMEN1KMT2A | |
| SCHEMBL28093181 | 0.83 | ALOX15 (0.38) | HMGCRTYRMAPTHTTMEN1 | |
| SCHEMBL5565377 | 0.82 | HMGCR (0.44) | HMGCRPTPN1PTPN11TYRCNR1 | |
| SCHEMBL1760537 | 0.74 | HMGCR (0.64) | HMGCRPTPN1PTPN11TYRCNR1 | |
| SCHEMBL28093183 | 0.74 | MEN1 (0.37) | MAPTMEN1KMT2ATDP1ALOX15 | |
| SCHEMBL11024762 | 0.72 | HMGCR (0.61) | HMGCRPTPN1PTPN11TYRCNR1 | |
| SCHEMBL28045776 | 0.71 | TYR (0.50) | HMGCRTYRMAPTHTTMEN1 | |
| SCHEMBL6268956 | 0.71 | HTT (0.49) | PTPN1CNR1CNR2HTTMEN1 | |
| SCHEMBL9056784 | 0.71 | TYR (0.50) | HMGCRTYRMAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924123-A | Methods and compositions for targeted protein degradation | 珃诺生物医药科技(杭州)有限公司 | 2022-01-11 | — | — | CN | disclosed |