Pyrrole

Pyrrole

SCHEMBL28093231

CC1CCc2ccc3c(ccc4ccccc43)c2C1.c1cc[nH]c1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HPRT1 P00492 1/20 0.37
CYP1A2 P05177 1/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
MAPT P10636 1/20 0.35
ACHE P22303 1/20 0.35
SLC6A2 P23975 1/20 0.35
AHR P35869 1/20 0.35
NFKB1 P19838 2/20 0.34
NFKB2 Q00653 2/20 0.34
RELA Q04206 2/20 0.34
HTR1D P28221 5/20 0.33
HTR1B P28222 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27289372 0.92 HPRT1 (0.44) ALDH1A1KDM4EHPRT1CYP1A2LCK
Pyrrole SCHEMBL28853016 0.90 HTR7 (0.40) ALDH1A1KDM4EHPRT1CYP1A2LCK
Furan SCHEMBL28125568 0.84 ALDH1A1 (0.39) ALDH1A1KDM4EHPRT1CYP1A2LCK
Pyrrole SCHEMBL28246464 0.84 NR2E1 (0.42) HPRT1
Phthalic Acid SCHEMBL27743950 0.82 NR4A1 (0.42) ALDH1A1KDM4ECYP1A2LCKFYN
Terephthalic Acid SCHEMBL27628972 0.81 KMT2A (0.44) ALDH1A1KDM4ECYP1A2MAPTNFKB1
Phthalic Anhydride SCHEMBL27566419 0.81 KDM4E (0.36) ALDH1A1KDM4EHPRT1CYP1A2MAPT
SCHEMBL27574172 0.80 HTR7 (0.45) ALDH1A1KDM4EHPRT1CYP1A2LCK
SCHEMBL28804604 0.80 CA1 (0.38) ALDH1A1KDM4EHPRT1CYP1A2LCK
Fluoride SCHEMBL27587185 0.79 HTR7 (0.44) ALDH1A1KDM4EHPRT1CYP1A2LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103937012-B The manufacture method of polylactic acid based resin microgranule, polylactic acid based resin microgranule and use the cosmetics of this microgranule 东丽株式会社 2016-08-24 CN disclosed