Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL27743950 | 0.91 | NR4A1 (0.42) | KMT2ANFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL27289372 | 0.88 | HPRT1 (0.44) | NFKB1NFKB2RELAALDH1A1MAPT | |
| Terephthalic Acid SCHEMBL27628973 | 0.85 | NFKB1 (0.38) | NFKB1NFKB2RELAALDH1A1MAPT | |
| Pyrrole SCHEMBL28093231 | 0.81 | ALDH1A1 (0.39) | NFKB1NFKB2RELAALDH1A1MAPT | |
| Furan SCHEMBL28125568 | 0.81 | ALDH1A1 (0.39) | NFKB1NFKB2RELAALDH1A1MAPT | |
| Phthalic Anhydride SCHEMBL27566419 | 0.81 | KDM4E (0.36) | NFKB1NFKB2RELAALDH1A1MAPT | |
| SCHEMBL28804604 | 0.80 | CA1 (0.38) | NFKB1NFKB2RELAALDH1A1MAPT | |
| Terephthalic Acid SCHEMBL27482447 | 0.79 | RXRA (0.44) | KMT2AALDH1A1MAPTHPGDCYP1A2 | |
| SCHEMBL27574172 | 0.77 | HTR7 (0.45) | ALDH1A1MAPTKDM4ECYP1A2 | |
| Benzoic Acid SCHEMBL27487417 | 0.77 | WDR5 (0.41) | NFKB1NFKB2RELAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1800979-B | Solder resist composition of light-curing single liquid style and printing circuit board use same | TAIYO INK MFG CO LTD | 2014-05-14 | — | — | CN | disclosed |
| CN-1800979-A | Solder resist composition of light-curing single liquid style and printing circuit board use same | SEIKO INSTR INC (JP) | 2006-07-12 | — | — | CN | disclosed |