Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.30 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9835383 | 0.74 | ALDH1A1 (0.34) | KDM4EKMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10272925 | 0.69 | CYP2D6 (0.54) | KDM4EKMT2ACYP2C19CYP2D6MAPK1 | |
| SCHEMBL600160 | 0.66 | GPR84 (0.35) | KDM4EKMT2AMAPK1HTTLMNA | |
| SCHEMBL13313250 | 0.65 | ALDH1A1 (0.56) | KDM4EKMT2ACYP2C19CYP2D6MAPK1 | |
| SCHEMBL11567090 | 0.65 | KDM4E (0.36) | KDM4EKMT2ACYP2C19CYP2D6MAPK1 | |
| SCHEMBL2937356 | 0.65 | TSHR (0.37) | KDM4EKMT2ACYP2C19CYP2D6HTT | |
| SCHEMBL3891060 | 0.65 | ALDH1A1 (0.32) | KDM4EKMT2ALMNAALDH1A1MAPT | |
| SCHEMBL3068255 | 0.65 | TSHR (0.41) | KDM4EKMT2ACYP2C19MAPK1HTT | |
| SCHEMBL13490805 | 0.64 | LMNA (0.49) | KDM4EKMT2AMAPK1HTTLMNA | |
| SCHEMBL27857265 | 0.64 | CYP17A1 (0.36) | KDM4EKMT2ACYP2C19MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965166-B | Rabeprazole intermediate impurities 2-{ [4-(3-methoxy propoxy)-3-oxide of mathylpyridine-2-base] methyl sulfur } preparation method of-1H-benzimidazole | 东南大学 | 2016-08-17 | — | — | CN | disclosed |