Diphenylmethane

Diphenylmethane

SCHEMBL28093285

O=CO.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.67
PLA2G10 O15496 1/20 0.52
PLA2G2A P14555 1/20 0.52
LMNA P02545 1/20 0.52
IDH1 O75874 1/20 0.48
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH7 P40394 1/20 0.46
BCL2 P10415 1/20 0.46
BCL2L1 Q07817 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
AKR1B1 P15121 1/20 0.46
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.46
CYP2A6 P11509 1/20 0.46
CYP2C9 P11712 1/20 0.45
HNF4A P41235 1/20 0.45
SLC22A2 O15244 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL10394702 0.85 CALM1 (0.92) CALM1PLA2G10PLA2G2ALMNAIDH1
Formic Acid SCHEMBL28229876 0.83 FFAR1 (0.56) ALDH1A1CYP2A6HDAC8HDAC6MAPK1
Diphenylmethane SCHEMBL28288286 0.83 CALM1 (0.67) CALM1PLA2G10PLA2G2ALMNAIDH1
Diphenylmethane SCHEMBL29127396 0.82 CALM1 (0.75) CALM1PLA2G10PLA2G2ALMNAIDH1
Diphenylmethane SCHEMBL8658678 0.82 CALM1 (0.75) CALM1PLA2G10PLA2G2ALMNAIDH1
Diphenylmethane SCHEMBL5607610 0.82 CALM1 (0.75) CALM1PLA2G10PLA2G2ALMNAIDH1
Diphenylmethane SCHEMBL4361124 0.82 CALM1 (1.00) CALM1PLA2G10PLA2G2ALMNAIDH1
Diphenylmethane SCHEMBL3792579 0.82 CALM1 (1.00) CALM1PLA2G10PLA2G2ALMNAIDH1
Diphenylmethane SCHEMBL1303 0.82 CALM1 (1.00) CALM1PLA2G10PLA2G2ALMNAIDH1
Diphenylmethane SCHEMBL14763944 0.82 CALM1 (1.00) CALM1PLA2G10PLA2G2ALMNAIDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107250274-B Polyamide resin composition, method for producing polyamide resin composition, and molded article 旭化成株式会社 2021-02-02 CN disclosed
CN-112210208-A Polyamide resin composition and process for producing molded article 旭化成株式会社 2021-01-12 CN disclosed
CN-105980478-B Polyamide resin composition, method for producing polyamide resin composition, and molded article 旭化成株式会社 2018-07-24 CN disclosed
CN-104203815-B Surface-treated carbon nanotube and resin composition 旭化成株式会社 2017-02-15 CN disclosed
CN-103261156-B For treating the noval chemical compound of neurodegenerative disease 鲁汶天主教大学研究开发部 2016-12-28 CN disclosed
CN-105820560-A Molded article comprising polyamide resin composition 旭化成株式会社 2016-08-03 CN disclosed