Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28093672 | 1.00 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL28093694 | 0.78 | ESR2 (0.40) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL28093824 | 0.78 | ESR2 (0.40) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL14158459 | 0.76 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL27938004 | 0.76 | PGR (0.40) | ESR2KDM1AALDH1A1HPGDBCL2L1 | |
| SCHEMBL28085936 | 0.73 | ESR1 (0.35) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL28758384 | 0.72 | SLC6A2 (0.40) | — | |
| SCHEMBL27937898 | 0.69 | ESR2 (0.42) | ESR2METAP2KDM1AALDH1A1HPGD | |
| SCHEMBL28085897 | 0.68 | ESR2 (0.47) | ESR2KDM1AALDH1A1HPGDBCL2L1 | |
| SCHEMBL17591323 | 0.68 | HTR2B (0.46) | ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103596943-B | Hydantoin derivatives useful as KV3 inhibitors | 奥蒂福尼疗法有限公司 | 2016-10-12 | — | — | CN | disclosed |