Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702059 | 0.82 | HTT (0.46) | SLC6A2SLC6A4CYP2D6HTTSLC6A3 | |
| SCHEMBL13197463 | 0.81 | ALDH1A1 (0.51) | CYP2D6RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL15319337 | 0.80 | MTNR1A (0.40) | SLC6A4HTT | |
| SCHEMBL5497052 | 0.80 | HTT (0.45) | SLC6A2SLC6A4CYP2D6HTT | |
| SCHEMBL17193849 | 0.80 | LMNA (0.40) | SLC6A2SLC6A4CYP2D6SLC6A3NPC1 | |
| SCHEMBL6790140 | 0.80 | ADRA2A (0.53) | SLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL7271833 | 0.80 | SLC6A2 (0.37) | SLC6A2SLC6A4CYP2D6HTTSLC6A3 | |
| SCHEMBL9683908 | 0.80 | LMNA (0.40) | SLC6A2SLC6A4CYP2D6SLC6A3NPC1 | |
| SCHEMBL29932054 | 0.80 | SLC6A2 (0.38) | SLC6A2SLC6A4CYP2D6SLC6A3NPC1 | |
| SCHEMBL17193848 | 0.80 | LMNA (0.40) | SLC6A2SLC6A4CYP2D6SLC6A3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |