Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MDH1 | P40925 | 1/20 | 0.39 |
| ▸ | MDH2 | P40926 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124033 | 0.84 | SERPINE1 (0.55) | SERPINE1MEN1KMT2APOLBGAA | |
| SCHEMBL422675 | 0.84 | SERPINE1 (0.58) | SERPINE1STSMEN1KMT2APOLB | |
| SCHEMBL28197968 | 0.83 | HIF1A (0.55) | SERPINE1MEN1KMT2APOLBGAA | |
| SCHEMBL2388331 | 0.82 | HIF1A (0.49) | SERPINE1MEN1KMT2APOLBGAA | |
| SCHEMBL28094061 | 0.80 | STS (0.46) | SERPINE1STSMEN1KMT2APOLB | |
| SCHEMBL9126429 | 0.79 | HIF1A (0.60) | SERPINE1MEN1KMT2AHIF1AEPAS1 | |
| SCHEMBL7501343 | 0.77 | HIF1A (0.48) | SERPINE1MEN1KMT2AHIF1AEPAS1 | |
| SCHEMBL27847928 | 0.77 | MEN1 (0.59) | SERPINE1MEN1KMT2APOLBGAA | |
| SCHEMBL2747091 | 0.75 | SERPINE1 (0.50) | SERPINE1STSMEN1KMT2AHIF1A | |
| SCHEMBL28094159 | 0.75 | FAAH (0.53) | STSMEN1KMT2AHIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220600-A | Flavone derivatives and its production and use | 厦门大学 | 2016-12-14 | — | — | CN | claimed |