SCHEMBL2388331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9126429	0.83	HIF1A (0.60)	HIF1AEPAS1SERPINE1KMT2AMEN1
	SCHEMBL28094060	0.82	SERPINE1 (0.50)	HIF1AEPAS1SERPINE1KMT2AMEN1
	SCHEMBL7501343	0.81	HIF1A (0.48)	HIF1AEPAS1SERPINE1KMT2AMEN1
	SCHEMBL9124033	0.79	SERPINE1 (0.55)	HIF1AEPAS1SERPINE1KMT2AMEN1
	SCHEMBL422675	0.79	SERPINE1 (0.58)	HIF1AEPAS1SERPINE1KMT2AMEN1
	SCHEMBL28197968	0.78	HIF1A (0.55)	HIF1AEPAS1SERPINE1KMT2AMEN1
	SCHEMBL27847928	0.73	MEN1 (0.59)	HIF1AEPAS1SERPINE1KMT2AMEN1
	SCHEMBL417009	0.72	RAB9A (0.53)	HIF1AEPAS1KMT2AMEN1RAB9A
	SCHEMBL9124063	0.72	HIF1A (0.51)	HIF1AEPAS1SERPINE1KMT2AMEN1
	SCHEMBL28906363	0.72	RARA (0.56)	KMT2AMEN1CNR2EPHX2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.