Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | MYC | P01106 | 2/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27856092 | 0.80 | MYC (0.34) | MYCNR4A1HSD17B3HPGDLMNA | |
| SCHEMBL11516330 | 0.77 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4MYC | |
| SCHEMBL27516784 | 0.75 | MAOA (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27746292 | 0.74 | GAA (0.33) | ALDH1A1KMT2A | |
| SCHEMBL29221326 | 0.73 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4MYC | |
| SCHEMBL27780815 | 0.71 | MEN1 (0.35) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL27856087 | 0.70 | CYP11B1 (0.49) | — | |
| SCHEMBL1165819 | 0.69 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4MYC | |
| SCHEMBL27780820 | 0.69 | ALDH1A1 (0.32) | NOTUMHSD17B3ALDH1A1LMNAKMT2A | |
| SCHEMBL27516301 | 0.69 | ALDH1A1 (0.33) | NOTUMHSD17B3ALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965136-B | A kind of method preparing N-methylthiazoline-2-ketone compounds | 苏州波菲特新材料科技有限公司 | 2016-09-07 | — | — | CN | disclosed |