Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780815 | 0.72 | MEN1 (0.35) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL28094908 | 0.69 | GRIA1 (0.39) | ALDH1A1LMNAKMT2AHSD17B3NOTUM | |
| SCHEMBL27034742 | 0.63 | GRIA1 (0.38) | LMNAMAPTMEN1KMT2AIDO1 | |
| SCHEMBL1049587 | 0.59 | GRIA1 (0.41) | LMNAMAPTMEN1KMT2AIDO1 | |
| SCHEMBL27499375 | 0.58 | GSK3B (0.38) | KMT2A | |
| SCHEMBL27652137 | 0.57 | IDO1 (0.57) | MAPTMEN1KMT2AIDO1BCHE | |
| SCHEMBL27516784 | 0.57 | MAOA (0.41) | ALDH1A1BCHE | |
| SCHEMBL13226849 | 0.57 | FNTA (0.34) | LMNAMAPTMEN1KMT2AIDO1 | |
| SCHEMBL28166968 | 0.56 | DRD2 (0.44) | LMNAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL13938144 | 0.55 | BCHE (0.54) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516889-B | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-101516889-A | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD (GB) | 2009-08-26 | — | — | CN | disclosed |