Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Fluoride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912717 | 0.95 | — | — | |
| Fluoride SCHEMBL8159283 | 0.95 | — | — | |
| Fluoride SCHEMBL5487749 | 0.95 | — | — | |
| Fluoride SCHEMBL28264643 | 0.90 | — | — | |
| Fluoride SCHEMBL28080228 | 0.90 | — | — | |
| Fluoride SCHEMBL5051050 | 0.90 | — | — | |
| Fluoride SCHEMBL28200025 | 0.90 | — | — | |
| Fluoride SCHEMBL8586978 | 0.90 | — | — | |
| Fluoride SCHEMBL28112618 | 0.90 | — | — | |
| Fluoride SCHEMBL28120059 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109713369-A | A kind of low cost aluminium base electrolyte and its aluminum cell application | 北京工业大学 | 2019-05-03 | — | — | CN | claimed |
| CN-106458946-A | Dehydration of a sugar alcohol with mixed combination of acid catalysts | 阿彻丹尼尔斯米德兰德公司 | 2017-02-22 | — | — | CN | claimed |
| CN-103814005-B | Process for producing p-xylene and terephthalic acid | 微麦德斯公司 | 2017-12-29 | — | — | CN | disclosed |
| CN-107492659-A | Aluminium-sulfur battery and its preparation method and application | 北京理工大学 | 2017-12-19 | — | — | CN | disclosed |
| CN-104755466-B | The preparation of dihydroxy ethyl piperazine | 陶氏环球技术有限责任公司 | 2016-08-17 | — | — | CN | disclosed |