Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Fluoride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL14562536 | 1.00 | — | — | |
| Fluoride SCHEMBL5487749 | 0.95 | — | — | |
| Fluoride SCHEMBL8159283 | 0.95 | — | — | |
| SCHEMBL7057927 | 0.95 | CA2 (0.54) | — | |
| SCHEMBL564772 | 0.95 | — | — | |
| SCHEMBL28364296 | 0.95 | — | — | |
| SCHEMBL30427518 | 0.90 | — | — | |
| Fluoride SCHEMBL5051050 | 0.90 | — | — | |
| SCHEMBL20952510 | 0.90 | — | — | |
| Fluoride SCHEMBL8586978 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408003-B | The separation carried out using ion liquid solvent | 切弗朗菲利浦化学公司 | 2018-06-12 | — | — | CN | claimed |
| CN-105237549-B | A kind of synthetic method of sirolimus 40- ether derivants | 浙江医药股份有限公司新昌制药厂 | 2018-03-09 | — | — | CN | claimed |
| CN-107474034-A | Method for preparing carbocyclic ring sugar derivatives | 瑞沙恩医药公司 | 2017-12-15 | — | — | CN | claimed |
| CN-105330662-B | Preparation of imidazole type ionic liquid derived by cinchona alkaloid | 华东师范大学 | 2017-05-24 | — | — | CN | claimed |
| CN-107082771-B | Double alpha-cyano imines substituted isochroman class compounds and its synthetic method | 上海大学 | 2019-11-19 | — | — | CN | disclosed |
| CN-110183352-A | β-carbonyl-(alpha-cyano imines) class compound and its synthetic method | 上海大学 | 2019-08-30 | — | — | CN | disclosed |
| CN-109879873-A | Tetrahydro dibenzo naphthyridine compounds and its synthetic method and application | 广西师范大学 | 2019-06-14 | — | — | CN | disclosed |
| CN-104692985-B | Palladium chtalyst synthesizes alpha-aromatic, heteroaryl or alkenyl-α, α-difluoro allylic structure method | 中国科学院上海有机化学研究所 | 2019-05-17 | — | — | CN | disclosed |
| CN-109438349-A | 6- (alpha-cyano imines) base phenanthridines class compound and its synthetic method | 上海大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-106167459-B | A method of synthesis alkenyl thiocyanates derivative | 华南理工大学 | 2018-09-14 | — | — | CN | disclosed |
| CN-107922432-A | Novel hydroxy acid derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2018-04-17 | — | — | CN | disclosed |
| CN-105217749-B | A kind of absorption carrier of loading nano silvery and preparation method thereof | 何素梅 | 2018-03-13 | — | — | CN | disclosed |
| CN-106233487-B | Composition and light-emitting element using same | 住友化学株式会社 | 2017-11-17 | — | — | CN | disclosed |
| CN-103889974-B | Radiolabeled compound and they in mammal as phosphodiesterase (PDE10A) quantitative imaging radiotracer purposes | 武田药品工业株式会社 | 2017-10-03 | — | — | CN | disclosed |
| CN-103906758-B | Glycoside compound, method for producing thioether, ether, method for producing glycoside compound, and method for producing nucleic acid | 株式会社博纳克 | 2017-05-10 | — | — | CN | disclosed |
| CN-106661322-A | Polyketone resin composition having excellent oil resistance | 株式会社晓星 | 2017-05-10 | — | — | CN | disclosed |
| CN-106604950-A | Polyketone resin composition having outstanding water resistance | 株式会社晓星 | 2017-04-26 | — | — | CN | disclosed |
| CN-103965165-B | A kind of isoquinoline compound suppressing IAP and preparation method and application | 复旦大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-106233487-A | Composition and light-emitting element using same | 住友化学株式会社 | 2016-12-14 | — | — | CN | disclosed |
| CN-103339753-B | Organic semiconductor component with doped hole conductor layer | 西门子公司 | 2016-11-09 | — | — | CN | disclosed |