Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | NPM1 | P06748 | 2/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21803208 | 0.81 | KDM4E (0.51) | CYP11B1CYP11B2MAPTCYP1A2HTT | |
| SCHEMBL2016383 | 0.78 | PPARG (0.40) | CYP11B1CYP11B2NPM1ALKMAPT | |
| SCHEMBL2013679 | 0.78 | PPARG (0.45) | PPARGHTTACSS2MEN1KMT2A | |
| SCHEMBL12210156 | 0.76 | MEN1 (0.44) | NPM1ALKMAPTPPARGCYP1A2 | |
| SCHEMBL28326451 | 0.75 | HTT (0.62) | MAPTCYP1A2CYP2D6HTTMEN1 | |
| SCHEMBL22031586 | 0.75 | GLA (0.49) | PPARGMEN1KMT2AKDM4E | |
| SCHEMBL15112162 | 0.75 | MCHR1 (0.45) | ACSS2 | |
| SCHEMBL25149332 | 0.73 | CDK9 (0.47) | SOS1NPM1ALKPDE2AMAPT | |
| SCHEMBL31113507 | 0.73 | CDK9 (0.47) | SOS1NPM1ALKPDE2AMAPT | |
| SCHEMBL22031600 | 0.73 | CACNA2D1 (0.44) | PPARGACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103739605-B | For detecting the developer of neurological disorder | 伊莱利利公司 | 2016-08-17 | — | — | CN | disclosed |