SCHEMBL28095208

SCHEMBL28095208

Fc1cc(Br)ccc1OCN1CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
ALDH1A1 P00352 3/20 0.45
POLB P06746 2/20 0.45
TSHR P16473 2/20 0.45
LMNA P02545 2/20 0.45
HTT P42858 1/20 0.45
PKM P14618 1/20 0.43
LTA4H P09960 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CCR5 P51681 1/20 0.42
GFER P55789 1/20 0.42
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ATM Q13315 1/20 0.41
HPGD P15428 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL226018 0.85 LTA4H (0.60) KDM4ETDP1L3MBTL1ALDH1A1POLB
SCHEMBL227430 0.85 LTA4H (0.60) KDM4ETDP1L3MBTL1ALDH1A1POLB
SCHEMBL1775142 0.84 ALDH1A1 (0.57) KDM4EL3MBTL1ALDH1A1LMNALTA4H
SCHEMBL1776658 0.84 ALDH1A1 (0.57) KDM4EL3MBTL1ALDH1A1LMNALTA4H
SCHEMBL3575918 0.84 ALDH1A1 (0.57) KDM4EL3MBTL1ALDH1A1LMNALTA4H
SCHEMBL2322184 0.83 LTA4H (0.61) KDM4ETDP1ALDH1A1POLBLMNA
SCHEMBL1821648 0.82 KDM4E (0.57) KDM4EL3MBTL1ALDH1A1LMNALTA4H
SCHEMBL12726046 0.76 LTA4H (0.44) KDM4ETDP1ALDH1A1LTA4HMEN1
SCHEMBL1776537 0.73 L3MBTL1 (0.44) KDM4EL3MBTL1ALDH1A1LMNALTA4H
SCHEMBL1427498 0.72 KDM4E (0.70) KDM4ETDP1ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105873916-A Amide derivatives for GPR119 agonists 株式会社钟根堂 2016-08-17 CN disclosed