Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3573539 | 0.84 | HRH3 (0.59) | HRH3ATML3MBTL1KDM4EHTT | |
| SCHEMBL13033227 | 0.79 | ATM (0.68) | ATML3MBTL1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL3163559 | 0.76 | HRH3 (0.63) | CXCR1LTA4HHRH3ATMESR1 | |
| SCHEMBL4178236 | 0.73 | HRH3 (0.42) | CXCR1LTA4HHRH3ESR1ESR2 | |
| SCHEMBL4664868 | 0.72 | SMN1; SMN2 (0.51) | LTA4HL3MBTL1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL15806741 | 0.72 | EGFR (0.42) | SMN1; SMN2NSD2NSD3 | |
| SCHEMBL28095208 | 0.72 | KDM4E (0.49) | LTA4HATML3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL538363 | 0.72 | ALDH1A1 (0.54) | CXCR1LTA4HHRH3KDM4ESMN1; SMN2 | |
| SCHEMBL17366239 | 0.71 | NSD2 (0.41) | SMN1; SMN2NSD2NSD3 | |
| SCHEMBL990744 | 0.71 | HTT (0.41) | CXCR1LTA4HHRH3ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873916-A | Amide derivatives for GPR119 agonists | 株式会社钟根堂 | 2016-08-17 | — | — | CN | disclosed |