Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 7/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186127 | 0.85 | SNCA (0.33) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3040195 | 0.81 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AMAPTUSP2 | |
| SCHEMBL28095574 | 0.77 | CDC25A (0.40) | ALDH1A1CDC25AMEN1KMT2AMAPT | |
| SCHEMBL4191633 | 0.76 | DRD2 (0.36) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4193155 | 0.76 | PRNP (0.33) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4192299 | 0.75 | HDAC4 (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7049435 | 0.73 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4178444 | 0.72 | HDAC4 (0.37) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4192625 | 0.72 | HDAC4 (0.37) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL38665521 | 0.71 | HDAC4 (0.49) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101918367-B | Acridine compounds Facile N-alkylation in ionic liquid | 西门子医疗保健诊断公司 | 2016-08-24 | — | — | CN | disclosed |