Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28095230 | 0.81 | ALDH1A1 (0.36) | ALDH1A1CYP3A4HSD17B10MAPTUSP2 | |
| SCHEMBL4186127 | 0.79 | SNCA (0.33) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL4178414 | 0.70 | PRNP (0.33) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL38664719 | 0.69 | ATM (0.40) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL38663301 | 0.68 | HDAC4 (0.41) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL38665317 | 0.67 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4191633 | 0.66 | DRD2 (0.36) | HSP90AA1MEN1KMT2A | |
| SCHEMBL12096594 | 0.65 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3036376 | 0.65 | HPGD (0.34) | MAPTMEN1KMT2A | |
| SCHEMBL4192299 | 0.65 | HDAC4 (0.40) | ALDH1A1CYP1A2CYP2C19HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1946108-B1 | HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2014-10-01 | — | — | EP | disclosed |
| US-7785904-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20080014660-A1 | High Quantum Yield Acridinium Compounds and Their Uses in Improving Assay Sensitivity | BAYER HEALTHCARE LLC | 2008-01-17 | — | — | US | disclosed |
| US-7309615-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) | 2007-12-18 | — | — | US | disclosed |
| US-20050221390-A1 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | BAYER HEALTHCARE LLC (US) | 2005-10-06 | — | — | US | disclosed |