Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16020852 | 0.93 | LMNA (0.47) | ERN1LMNACA12CA1CA2 | |
| SCHEMBL7661459 | 0.87 | CA12 (0.47) | ERN1LMNACA12CA1CA2 | |
| SCHEMBL15145284 | 0.86 | LMNA (0.59) | ERN1LMNACA12CA1CA2 | |
| SCHEMBL18199319 | 0.84 | ERN1 (0.50) | ERN1LMNACA12CA1CA2 | |
| SCHEMBL13127068 | 0.84 | LTA4H (0.46) | ERN1ALDH1A1 | |
| SCHEMBL25374930 | 0.83 | CA1 (0.48) | ERN1LMNACA12CA1CA2 | |
| SCHEMBL1498751 | 0.83 | LMNA (0.40) | ERN1LMNAPRKDCALDH1A1TRIM24 | |
| SCHEMBL20892596 | 0.82 | ALDH1A1 (0.67) | ERN1DPP4ALDH1A1TRIM24TYR | |
| SCHEMBL30091707 | 0.81 | LMNA (0.43) | ERN1LMNAPRKDCHDAC8ALDH1A1 | |
| SCHEMBL22272552 | 0.81 | LMNA (0.43) | ERN1LMNAPRKDCHDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186845-B | S1P receptor modulators and their purposes | 阿卡制药有限公司 | 2016-09-07 | — | — | CN | disclosed |