Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.48 |
| ▸ | PRKDC | P78527 | 14/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | XRCC6 | P12956 | 1/20 | 0.43 |
| ▸ | XRCC5 | P13010 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28095884 | 0.84 | PIK3CB (0.48) | PIK3CAPIK3CDPIK3CGP2RY12PRKDC | |
| SCHEMBL28095991 | 0.82 | PIK3CB (0.48) | PIK3CAPIK3CDPIK3CGP2RY12PRKDC | |
| SCHEMBL28946196 | 0.80 | PIK3CA (0.50) | PIK3CAPIK3CDPIK3CGP2RY12PRKDC | |
| SCHEMBL24714393 | 0.76 | PRKDC (0.59) | PIK3CAPIK3CDPIK3CGP2RY12PRKDC | |
| SCHEMBL28095889 | 0.75 | PIK3CB (0.67) | PIK3CAPIK3CDPIK3CG | |
| SCHEMBL1638958 | 0.73 | PIK3CA (0.53) | PIK3CAPIK3CDPIK3CGPRKDCPIK3R1 | |
| SCHEMBL13449184 | 0.72 | PRKDC (0.58) | PIK3CAPIK3CDPIK3CGP2RY12PRKDC | |
| SCHEMBL15541001 | 0.72 | PRKDC (0.71) | PIK3CAPIK3CDPIK3CGPRKDCPIK3R1 | |
| SCHEMBL1638322 | 0.72 | PRKDC (0.55) | PIK3CAPIK3CDPIK3CGP2RY12PRKDC | |
| SCHEMBL28946192 | 0.72 | P2RY12 (0.53) | PIK3CAPIK3CDPIK3CGP2RY12PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447657-B | There is the chromene ketone derivatives of anti-tumor activity | 阿斯利康(瑞典)有限公司 | 2016-08-17 | — | — | CN | disclosed |