Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542970 | 0.84 | ELANE (0.57) | F2PRSS1PRSS2PRSS3MEN1 | |
| SCHEMBL6284986 | 0.83 | KMT2A (0.64) | F2PRSS1PRSS2PRSS3MEN1 | |
| SCHEMBL13650268 | 0.83 | MEN1 (0.48) | F2PRSS1PRSS2PRSS3MEN1 | |
| SCHEMBL5562888 | 0.81 | MEN1 (0.47) | F2PRSS1PRSS2PRSS3MEN1 | |
| SCHEMBL1835776 | 0.81 | RAB9A (0.53) | MEN1KMT2AKIF11ELANE | |
| SCHEMBL3809052 | 0.81 | LMNA (0.57) | F2PRSS1PRSS2PRSS3MEN1 | |
| SCHEMBL23174993 | 0.81 | MEN1 (0.47) | F2PRSS1PRSS2PRSS3MEN1 | |
| SCHEMBL11375700 | 0.79 | PRSS1 (0.56) | PRSS1MEN1KMT2AKIF11 | |
| Hydrochloric Acid SCHEMBL11168858 | 0.79 | LMNA (0.55) | F2PRSS1PRSS2PRSS3MEN1 | |
| SCHEMBL21464418 | 0.79 | SLC6A4 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106046100-A | 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl derivatives, methods for the production thereof and the use thereof for treating diseases | 拜耳知识产权有限责任公司 | 2016-10-26 | — | — | CN | claimed |
| CN-102596985-B | 17-hydroxy-17-pentafluoroethyl-estra-4, 9(10) -dien-11-aryl derivatives, method for the production thereof and use thereof for treating diseases | 拜耳知识产权有限责任公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-106046100-A | 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl derivatives, methods for the production thereof and the use thereof for treating diseases | 拜耳知识产权有限责任公司 | 2016-10-26 | — | — | CN | disclosed |