Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31586107 | 0.79 | LRRK2 (0.47) | PDK2PDK4 | |
| SCHEMBL1796396 | 0.76 | AAK1 (0.40) | AAK1 | |
| SCHEMBL22525223 | 0.72 | PDK2 (0.46) | PDK2PDK4PDK1 | |
| SCHEMBL25304749 | 0.71 | AURKA (0.46) | AAK1 | |
| SCHEMBL19667381 | 0.69 | PDK2 (0.44) | PDK2PDK4PDK1 | |
| SCHEMBL19306614 | 0.69 | PDK2 (0.49) | PDK2PDK4PDK1 | |
| SCHEMBL5925906 | 0.68 | LMNA (0.40) | — | |
| SCHEMBL22883506 | 0.64 | PDK2 (0.36) | PDK2PDK4 | |
| SCHEMBL7842455 | 0.64 | PARP1 (0.36) | — | |
| SCHEMBL18874539 | 0.64 | ALDH1A1 (0.40) | PDK2PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008512-B | E1 activating enzyme inhibitors | 千禧药品公司 | 2019-03-12 | — | — | CN | disclosed |
| CN-106008512-A | INHIBITORS OF E1 ACTIVATING ENZYMES | 千禧药品公司 | 2016-10-12 | — | — | CN | disclosed |