Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979569 | 0.84 | DRD4 (0.47) | SIGMAR1DRD2KDM4ELMNAMAPT | |
| SCHEMBL27914131 | 0.84 | SIGMAR1 (0.57) | SIGMAR1HTR1ADRD2MAPT | |
| SCHEMBL27801629 | 0.84 | KDM4E (0.56) | SIGMAR1HTR1ADRD2KDM4ELMNA | |
| SCHEMBL10241118 | 0.82 | SIGMAR1 (0.57) | SIGMAR1HTR1ADRD2PPARGPPARA | |
| SCHEMBL27831844 | 0.81 | KDM4E (0.41) | SIGMAR1HTR1ADRD2KDM4ELMNA | |
| SCHEMBL27712204 | 0.80 | KDM4E (0.43) | SIGMAR1HTR1ADRD2KDM4ELMNA | |
| SCHEMBL9531074 | 0.80 | SIGMAR1 (0.74) | SIGMAR1HTR1ADRD2PPARGPPARA | |
| SCHEMBL27945231 | 0.79 | KDM4E (0.41) | SIGMAR1DRD2KDM4ELMNAMAPT | |
| SCHEMBL23277150 | 0.78 | KDM4E (0.49) | SIGMAR1HTR1ADRD2KDM4ELMNA | |
| SCHEMBL20582537 | 0.77 | PPARG (0.45) | SIGMAR1KDM4EPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061963-A | Heterocyclic modulators of lipid synthesis and combinations thereof | 3-V生物科学股份有限公司 | 2016-10-26 | — | — | CN | disclosed |