Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 16/20 | 0.74 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589688 | 0.86 | SIGMAR1 (0.72) | SIGMAR1HTR1A | |
| SCHEMBL9879618 | 0.85 | SIGMAR1 (1.00) | SIGMAR1DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9874846 | 0.84 | SIGMAR1 (0.97) | SIGMAR1DRD2HTR1A | |
| SCHEMBL5771973 | 0.82 | DRD2 (0.69) | SIGMAR1DRD2HTR1APPARGPPARA | |
| SCHEMBL28096230 | 0.80 | SIGMAR1 (0.57) | SIGMAR1DRD2HTR1APPARGPPARA | |
| SCHEMBL4493623 | 0.80 | SIGMAR1 (0.55) | SIGMAR1DRD2HTR1APPARGPPARA | |
| SCHEMBL13211790 | 0.79 | DRD2 (0.81) | SIGMAR1DRD2HTR1A | |
| SCHEMBL7957644 | 0.79 | DRD2 (0.61) | SIGMAR1DRD2HTR1APPARGPPARA | |
| Hydrochloric Acid SCHEMBL9092965 | 0.79 | SIGMAR1 (0.77) | SIGMAR1DRD2HTR1A | |
| SCHEMBL11938943 | 0.78 | SIGMAR1 (0.65) | SIGMAR1DRD2HTR1APPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |