Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2347397 | 0.78 | HCAR2 (0.53) | KDM4EMAPK1LMNAGABRPGABRD | |
| SCHEMBL5704861 | 0.78 | HCAR2 (0.53) | KDM4EMAPK1LMNAGABRPGABRD | |
| SCHEMBL11501260 | 0.76 | PTGS2 (0.55) | KDM4EMAPTGAAMAPK1ALDH1A1 | |
| SCHEMBL22753334 | 0.74 | CYP2A6 (0.43) | KDM4EMAPTL3MBTL1GAAALDH1A1 | |
| SCHEMBL11439819 | 0.73 | ATG4B (0.45) | KDM4EMAPK1ALDH1A1LMNAHTT | |
| SCHEMBL11439822 | 0.73 | ATG4B (0.45) | KDM4EMAPK1ALDH1A1LMNAHTT | |
| Acetic Acid SCHEMBL11525074 | 0.73 | PANK3 (0.49) | KDM4EMAPTL3MBTL1GAAMAPK1 | |
| SCHEMBL2575820 | 0.73 | PTGS2 (0.55) | KDM4EMAPTL3MBTL1GAAALDH1A1 | |
| SCHEMBL8223856 | 0.73 | PTGS2 (0.55) | KDM4EMAPTL3MBTL1GAAALDH1A1 | |
| SCHEMBL11115420 | 0.73 | PARP15 (0.47) | KDM4EMAPTGAAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347864-B | Pyrimidone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA 2 | 葛兰素集团有限公司 | 2016-08-10 | — | — | CN | disclosed |