Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28096276

CC(=O)OCCC(N)C(=O)O.S

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 4/20 0.50
NOS1 P29475 4/20 0.50
NOS2 P35228 4/20 0.50
SLC1A3 P43003 3/20 0.45
SLC1A2 P43004 3/20 0.45
SLC1A1 P43005 3/20 0.45
GRIK1 P39086 2/20 0.45
GRIK2 Q13002 2/20 0.45
GSR P00390 2/20 0.45
CYP1A2 P05177 2/20 0.45
SLC7A5 Q01650 1/20 0.45
GRM8 O00222 1/20 0.45
GRM6 O15303 1/20 0.45
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
GRM5 P41594 1/20 0.45
GRIA1 P42261 1/20 0.45
GRIA2 P42262 1/20 0.45
GRIA3 P42263 1/20 0.45
GRIA4 P48058 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL180571 0.98 NOS3 (0.51) NOS3NOS1NOS2SLC1A3SLC1A2
SCHEMBL302495 0.98 NOS3 (0.51) NOS3NOS1NOS2SLC1A3SLC1A2
Hydrochloric Acid SCHEMBL30019097 0.96 NOS1 (0.50) NOS3NOS1NOS2SLC1A3SLC1A2
Methane SCHEMBL3379702 0.96 NOS3 (0.50) NOS3NOS1NOS2SLC1A3SLC1A2
Methane SCHEMBL3379696 0.96 NOS3 (0.50) NOS3NOS1NOS2SLC1A3SLC1A2
Acetic Acid SCHEMBL30975324 0.96 NOS3 (0.50) NOS3NOS1NOS2SLC1A3SLC1A2
SCHEMBL30571193 0.96 NOS3 (0.50) NOS3NOS1NOS2SLC1A3SLC1A2
SCHEMBL4289326 0.94 NOS3 (0.49) NOS3NOS1NOS2SLC1A3SLC1A2
Homoserine SCHEMBL26118620 0.90 NOS3 (0.46) NOS3NOS1NOS2SLC1A3SLC1A2
Cysteine SCHEMBL15312673 0.89 PTGS1 (0.57) NOS3NOS1NOS2SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108026147-A Microorganism producing O-acetyl-homoserine and method for producing O-acetyl-homoserine using the same CJ第制糖株式会社 2018-05-11 CN claimed
CN-108026516-A Produced by the thio carboxylate dependence l-methionine of the albumen of fermentation 赢创德固赛有限公司 2018-05-11 CN claimed
CN-106062176-A Compositions and methods for biological production of amino acids in hydrogenotrophic microorganisms 特雷里斯公司 2016-10-26 CN claimed
CN-108138205-A O-acetylhomoserine sulfhydrylase variant and method for producing L-methionine using the same CJ第制糖株式会社 2018-06-08 CN disclosed
CN-108026516-A Produced by the thio carboxylate dependence l-methionine of the albumen of fermentation 赢创德固赛有限公司 2018-05-11 CN disclosed