SCHEMBL180571

SCHEMBL180571

CC(=O)OCC[C@H](N)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 4/20 0.51
NOS1 P29475 4/20 0.51
NOS2 P35228 4/20 0.51
SLC1A3 P43003 4/20 0.46
SLC1A2 P43004 4/20 0.46
SLC1A1 P43005 4/20 0.46
GRIK1 P39086 2/20 0.46
GRIK2 Q13002 2/20 0.46
GSR P00390 2/20 0.46
CYP1A2 P05177 2/20 0.46
SLC7A5 Q01650 1/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRM5 P41594 1/20 0.46
GRIA1 P42261 1/20 0.46
GRIA2 P42262 1/20 0.46
GRIA3 P42263 1/20 0.46
GRIA4 P48058 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL302495 1.00 NOS3 (0.51) NOS3NOS1NOS2SLC1A3SLC1A2
Hydrochloric Acid SCHEMBL30019097 0.98 NOS1 (0.50) NOS3NOS1NOS2SLC1A3SLC1A2
Methane SCHEMBL3379702 0.98 NOS3 (0.50) NOS3NOS1NOS2SLC1A3SLC1A2
SCHEMBL30571193 0.98 NOS3 (0.50) NOS3NOS1NOS2SLC1A3SLC1A2
Hydrogen Sulfide SCHEMBL28096276 0.98 NOS3 (0.50) NOS3NOS1NOS2SLC1A3SLC1A2
Acetic Acid SCHEMBL30975324 0.98 NOS3 (0.50) NOS3NOS1NOS2SLC1A3SLC1A2
Methane SCHEMBL3379696 0.98 NOS3 (0.50) NOS3NOS1NOS2SLC1A3SLC1A2
SCHEMBL4289326 0.96 NOS3 (0.49) NOS3NOS1NOS2SLC1A3SLC1A2
Homoserine SCHEMBL26118620 0.92 NOS3 (0.46) NOS3NOS1NOS2SLC1A3SLC1A2
Cysteine SCHEMBL15312673 0.91 PTGS1 (0.57) NOS3NOS1NOS2SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081266-A Recombinant O-acetyl-L-homoserine sulfhydryl transferase mutant, recombinant genetic engineering bacterium and application 2026-05-26 CN claimed
CN-122038497-A Method for improving fermentation efficiency of O-acetyl-L-homoserine 浙江工业大学 2026-05-15 CN claimed
US-12534747-B2 Microorganism producing L-amino acid and method of producing L-amino acid using the same CJ CHEILJEDANG CORPORATION (KR) 2026-01-27 US claimed
EP-4678760-A1 MICROORGANISM HAVING INCREASED ACTIVITY OF PYRUVATE DEHYDROGENASE COMPLEX SUBUNIT E1, AND METHOD FOR PRODUCING O-ACETYLHOMOSERINE OR DERIVATIVE THEREOF BY USING SAME CJ Cheiljedang Corporation (KR) 2026-01-14 EP claimed
US-12522808-B2 Modified polypeptide with attenuated activity of citrate synthase and method for producing L-amino acid using the same CJ Chieljedang Corporation (KR) 2026-01-13 US claimed
US-20260002183-A1 ENZYMATIC METHOD FOR PRODUCING L-GLUFOSINATE AND ITS PHOSPHOESTERS EVONIK OPERATIONS GMBH (DE) 2026-01-01 US claimed
EP-4667575-A1 MICROORGANISM WITH ENHANCED PYRUVATE DEHYDROGENASE COMPLEX DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE ACTIVITY AND METHOD FOR PRODUCING L-AMINO ACIDS USING SAME CJ CheilJedang Corporation (KR) 2025-12-24 EP claimed
US-20250361478-A1 O-ACETYL HOMOSERINE-PRODUCING MICROORGANISM AND METHOD FOR PRODUCING O-ACETYL HOMOSERINE OR L-METHIONINE USING SAME CJ CHEILJEDANG CORPORATION (KR) 2025-11-27 US claimed
US-12473558-B2 Promoter and use thereof CJ CHEILJEDANG CORPORATION (KR) 2025-11-18 US claimed
US-12378584-B2 Methionine analogue synthesis ENGENES BIOTECH GMBH (AT) 2025-08-05 US claimed
US-20060270013-A1 Method for the production of evolved microorganisms which permit the generation or modification of metabolic pathways METABOLIC EXPLORER (FR) 2006-11-30 US claimed
US-20060223149-A1 Methods for producing sulphurous fine chemicals BASF AKTIENGESELLSCHAFT 2006-10-05 US claimed
US-20060068476-A1 Method for the production by fermentation of sulphur-containing fine chemicals (metf) EVONIK OPERATIONS GMBH (DE) 2006-03-30 US claimed
US-20060003425-A1 Method for zymotic production of fine chemicals (meta) containing sulphur BASF AKTIENGESELLSCHAFT (DE) 2006-01-05 US claimed
EP-1597364-A2 METHOD FOR THE PRODUCTION OF EVOLVED MICROORGANISMS WHICH PERMIT THE GENERATION OR MODIFICATION OF METABOLIC PATHWAYS Metabolic Explorer (FR) 2005-11-23 EP claimed
CN-1653186-A Method for the fermentative production of sulfur-containing fine chemicals using metH-encoding coryneform bacteria BASF AG (DE) 2005-08-10 CN claimed
WO-2004076659-A2 METHOD FOR THE PRODUCTION OF EVOLVED MICROORGANISMS WHICH PERMIT THE GENERATION OR MODIFICATION OF METABOLIC PATHWAYS METABOLIC EXPLORER (FR) 2004-09-10 WO claimed
WO-2004021981-A2 METHODS FOR THE PREPARATION OF β-AMINO ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2004-03-18 WO claimed
US-20030113882-A1 Methods for the preparation of beta-amino acids WISCONSIN ALUMNI RESEARCH FOUNDATION 2003-06-19 US claimed
WO-1993017112-A1 BIOSYNTHESIS OF METHIONINE USING A REDUCED SOURCE OF SULFUR GENENCOR INTERNATIONAL, INC. (US) 1993-09-02 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534747-B2 Microorganism producing L-amino acid and method of producing L-amino acid using the same MTR, TST, AADAT NOS3 1474/4885NOS1 963/4885NOS2 914/4885
US-20260002183-A1 ENZYMATIC METHOD FOR PRODUCING L-GLUFOSINATE AND ITS PHOSPHOESTERS PGLS, GLO1, GLUL NOS3 3752/4885NOS1 3387/4885NOS2 3673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.