Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534783 | 1.00 | HSP90AA1 (0.55) | HSP90AA1ACMSDALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL10532966 | 0.98 | ACMSD (0.53) | HSP90AA1ACMSDALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL6981624 | 0.92 | MAPK1 (0.55) | HSP90AA1ACMSDALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7724414 | 0.87 | HSP90AA1 (0.51) | HSP90AA1ACMSDALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4574951 | 0.86 | MAPK1 (0.49) | HSP90AA1ACMSDALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL11213348 | 0.83 | HSP90AA1 (0.43) | HSP90AA1ACMSDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27038239 | 0.81 | MAPK1 (0.50) | HSP90AA1ALDH1A1MAPK1SMN1; SMN2TP53 | |
| SCHEMBL9510647 | 0.81 | NPBWR1 (0.49) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL2654454 | 0.81 | TDP1 (0.51) | HSP90AA1ACMSDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL26343168 | 0.80 | ACMSD (0.57) | HSP90AA1ACMSDALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105899497-A | Novel bis (hydroxyphenyl) benzoxazole compounds | 本州化学工业株式会社 | 2016-08-24 | — | — | CN | disclosed |