Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534783 | 0.83 | HSP90AA1 (0.55) | HSP90AA1ALDH1A1LMNAHTTRAB9A | |
| SCHEMBL9510647 | 0.83 | NPBWR1 (0.49) | ALDH1A1LMNAHTTRAB9AMAPT | |
| SCHEMBL28096306 | 0.83 | HSP90AA1 (0.55) | HSP90AA1ALDH1A1LMNAHTTRAB9A | |
| SCHEMBL2654454 | 0.83 | TDP1 (0.51) | HSP90AA1ALDH1A1LMNAHTTRAB9A | |
| SCHEMBL10532966 | 0.81 | ACMSD (0.53) | HSP90AA1ALDH1A1LMNAHTTRAB9A | |
| SCHEMBL9513666 | 0.81 | KMT2A (0.48) | ALDH1A1LMNARAB9AMAPTKMT2A | |
| SCHEMBL2551921 | 0.81 | TDP1 (0.53) | HSP90AA1ALDH1A1LMNAHTTRAB9A | |
| SCHEMBL7724414 | 0.80 | HSP90AA1 (0.51) | HSP90AA1ALDH1A1LMNAHTTRAB9A | |
| SCHEMBL26343168 | 0.80 | ACMSD (0.57) | HSP90AA1ALDH1A1LMNAHTTRAB9A | |
| Bicarbonate SCHEMBL7424111 | 0.79 | VCAM1 (0.49) | ALDH1A1LMNAHTTRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4419264-A | Fluorine-containing 4,4'-bis-(cyclohexyl)-biphenyl derivatives, and dielectrics and electro-optical display elements containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-12-06 | — | — | US | disclosed |