SCHEMBL28096904

SCHEMBL28096904

COc1c(F)cc(C(C)OC(C)=O)c(F)c1Br

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 3/20 0.35
ACACB O00763 1/20 0.33
TPMT P51580 1/20 0.32
PTPN1 P18031 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27860279 0.70 APLNR (0.38) ACACB
SCHEMBL28822260 0.68 SOS1 (0.42) TUBB1PTPN1
SCHEMBL22201771 0.67 CES2 (0.45)
SCHEMBL27930596 0.67 HTT (0.35)
SCHEMBL5759448 0.66 PRKDC (0.44) TUBB1
SCHEMBL10801932 0.66 TSHR (0.38)
SCHEMBL22241276 0.66 CES2 (0.46)
SCHEMBL27700199 0.66 CES2 (0.46)
SCHEMBL17380950 0.66 CES2 (0.46)
SCHEMBL27854073 0.65 MEN1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104011021-B heterocyclic derivatives and their use as prostaglandin D2 receptor modulators 埃科特莱茵药品有限公司 2016-08-24 CN disclosed