Chloroform

Chloroform

SCHEMBL28097024

ClC(Cl)Cl.[AsH2]c1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.45
ALDH1A1 P00352 3/20 0.33
MTOR P42345 1/20 0.32
RAB9A P51151 1/20 0.32
GRM7 Q14831 1/20 0.32
DPP4 P27487 2/20 0.32
BBOX1 O75936 1/20 0.32
EHMT2 Q96KQ7 1/20 0.32
EHMT1 Q9H9B1 1/20 0.32
F2 P00734 1/20 0.32
LMNA P02545 2/20 0.32
HIF1A Q16665 2/20 0.31
TRPA1 O75762 1/20 0.31
MAPK1 P28482 1/20 0.31
GSK3B P49841 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
ORAI1 Q96D31 1/20 0.30
ORAI2 Q96SN7 1/20 0.30
ORAI3 Q9BRQ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL456859 0.86
Bromide SCHEMBL28610589 0.82
Water SCHEMBL28363985 0.82
Bromide SCHEMBL11113762 0.82
SCHEMBL9438540 0.82
SCHEMBL4870608 0.75 TDP1 (0.36) TSHRLMNAHIF1ACYP3A4CYP1A2
Chlorobenzene SCHEMBL149324 0.69 TSHR (0.79) TSHRLMNAHIF1AMAPK1CYP3A4
Benzene SCHEMBL10484355 0.68 LMNA (0.57) TSHRALDH1A1LMNATDP1
Benzene SCHEMBL1744419 0.68 LMNA (0.57) TSHRALDH1A1LMNATDP1
Benzene SCHEMBL10484352 0.68 LMNA (0.57) TSHRALDH1A1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105866112-A Method for determining content of rhenium in rhenium-containing material 商洛学院 2016-08-17 CN disclosed