Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456859 | 0.80 | — | — | |
| Bromide SCHEMBL11113762 | 0.77 | — | — | |
| Bromide SCHEMBL28610589 | 0.77 | — | — | |
| Water SCHEMBL28363985 | 0.77 | — | — | |
| SCHEMBL9438540 | 0.77 | — | — | |
| Biphenyl SCHEMBL11779724 | 0.69 | ALDH1A1 (0.60) | TDP1TAAR1SLC6A4CYP1A2CYP3A4 | |
| Phenol SCHEMBL20741797 | 0.69 | CA12 (0.61) | TDP1TSHRCYP3A4 | |
| Anisole SCHEMBL11110211 | 0.67 | CA4 (0.74) | LMNATSHRACHECYP2A6DRD3 | |
| SCHEMBL664987 | 0.67 | — | — | |
| SCHEMBL184638 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381572-B2 | Reagents and procedures for multi-label high-specificity labeling | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2008-06-03 | — | — | US | disclosed |
| US-7282373-B2 | Ultra-high specificity fluorescent labeling | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-10-16 | — | — | US | disclosed |
| US-7141655-B2 | Reagents and procedures for high-specificity labeling | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2006-11-28 | — | — | US | disclosed |
| US-20060141531-A1 | Ultra-high specificity fluorescent labeling | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2006-06-29 | — | — | US | disclosed |
| US-20060141530-A1 | Using arsenic-mediated labeling to permit orthogonal molecule-specific, site-specific labeling of target molecules, such as proteins, with multiple labels; complex of peptide with tag of a cyanine dye having pendant 2,5-dithia-arsacyclopentane groups | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2006-06-29 | — | — | US | disclosed |
| US-20040019104-A1 | Reagents and procedures for high-specificity labeling | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2004-01-29 | — | — | US | disclosed |
| WO-2003107010-A1 | REAGENTS AND PROCEDURES FOR HIGH-SPECIFICITY LABELING | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060141531-A1 | Ultra-high specificity fluorescent labeling | RPS27A, RAET1L, QRFPR | TDP1 2886/4885TAAR1 1582/4885SLC6A2 2685/4885 |
| US-20060141530-A1 | Using arsenic-mediated labeling to permit orthogonal molecule-specific, site-specific labeling of target molecules, such as proteins, with multiple labels; complex of peptide with tag of a cyanine dye having pendant 2,5-dithia-arsacyclopentane groups | AS3MT, ARSA, PTMS | TDP1 722/4885TAAR1 401/4885SLC6A2 1548/4885 |
| US-20040019104-A1 | Reagents and procedures for high-specificity labeling | AS3MT, SRMS, HNRNPH3 | TDP1 908/4885TAAR1 179/4885SLC6A2 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.