Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568748 | 0.82 | ALDH1A1 (0.54) | LTA4HSMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL27922177 | 0.82 | LTA4H (0.47) | LTA4HSMN1; SMN2LMNAALDH1A1RAB9A | |
| SCHEMBL30617050 | 0.81 | LTA4H (0.59) | LTA4HSMN1; SMN2LMNAALDH1A1RAB9A | |
| SCHEMBL27943923 | 0.80 | PDE3B (0.48) | LTA4HCLK4SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2751117 | 0.79 | L3MBTL1 (0.59) | LTA4HCLK4SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2475247 | 0.79 | ALDH1A1 (0.51) | LTA4HSMN1; SMN2LMNAALDH1A1NPC1 | |
| Ammonia Solution, Strong SCHEMBL26627788 | 0.79 | PDE3B (0.47) | LTA4HCLK4SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL25986524 | 0.78 | LTA4H (0.81) | LTA4HSMN1; SMN2LMNAALDH1A1CYP2D6 | |
| SCHEMBL27884 | 0.78 | LTA4H (0.81) | LTA4HSMN1; SMN2LMNAALDH1A1CYP2D6 | |
| SCHEMBL1425001 | 0.78 | LTA4H (0.81) | LTA4HSMN1; SMN2LMNAALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137510-A | Compound | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-105916848-B | Kinase inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2018-01-09 | — | — | CN | disclosed |
| CN-105916848-A | Kinase inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2016-08-31 | — | — | CN | disclosed |